Purchasing Prograf doesn't have to be complicated or expensive. Ordering Prograf from Candrugstore, a trusted Canadian pharmacy, is not only more affordable but also highly convenient. You can place your order anytime—24 hours a day, seven days a week. To ensure timely delivery, which typically takes 2 to 4 weeks, it's a good idea to order early if you know you will need Prograf in the future.
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You can purchase up to a 90-day supply of Prograf to manage your medication needs. After placing your order, there's no need to pay immediately. We verify your prescription first, and a customer service representative will contact you to confirm payment
Description
Indications
Tacrolimus is administered in combination with other drugs to prevent the rejection of a transplanted kidney, heart, liver, or lung. This medicine falls into the category of drugs called immunosuppressants. Its mechanism of action involves suppressing your immune system, thereby weakening your body’s natural defense system. This enables your body to recognize and embrace the new organ as if it were an integral part of your own body.
Uses and Dosage
Tacrolimus is available in different forms, including capsules, granules for oral suspension, extended-release capsules, and extended-release tablets, all of which are taken orally. The immediate-release capsules and oral suspension are usually taken twice a day, 12 hours apart, either with or without food. The extended-release capsules or tablets are taken once a day on an empty stomach, at least an hour before breakfast or two hours after breakfast.
Take tacrolimus at the same time every day and follow the directions on your prescription label carefully. If you’re taking the granules for oral suspension, you should mix it with room temperature water before use and take it immediately. Don’t save any leftover mixture for later use.
The extended-release capsules and tablets should be swallowed whole with water and not crushed, chewed, or split.
Your doctor will monitor your progress closely and adjust your dosage as needed. Make sure to ask your doctor any questions you may have about the amount of tacrolimus you should take.
Continue taking tacrolimus even if you feel well, as it’s the only way to prevent rejection of your transplant. Do not stop taking tacrolimus without consulting your doctor.
Different tacrolimus products release the medication differently in your body and cannot be used interchangeably. Only take the tacrolimus product prescribed by your doctor and do not switch to a different product unless your doctor advises it.
Side Effects
Some side effects may occur that usually do not need medical attention:
headache
diarrhea
constipation
nausea
vomiting
heartburn
stomach pain
difficulty falling asleep or staying asleep
dizziness
weakness
back or joint pain
burning, numbness, pain, or tingling in the hands or feet
Inform your healthcare provider immediately if you experience any serious side effects:
decreased urination
pain or burning on urination
hives, rash, or itching
pale skin, shortness of breath, or fast heartbeat
extreme tiredness
swelling of the arms, hands, feet, ankles, or lower legs; or shortness of breath
unusual bleeding or bruising
seizures
vision changes
confusion
uncontrollable shaking of a part of the body
coma (loss of consciousness for a period of time)
pinpoint-sized purple dots under the skin
bruising, fever, tiredness, sleepiness, confusion, yellowing of skin or eyes
Caution
Prior to taking tacrolimus, inform your doctor or pharmacist if you have any allergies, including allergies to macrolide medications like sirolimus, or any other allergies. This product may contain inactive ingredients that can cause allergic reactions or other complications.
Before using tacrolimus, disclose your medical history, especially if you have had mineral imbalances like high potassium, kidney disease, recent or current infections, cancer, liver disease, high blood pressure, or diabetes.
Tacrolimus may cause QT prolongation, which affects the heart rhythm. This condition can cause serious symptoms like fast or irregular heartbeat or severe dizziness and fainting, which require immediate medical attention.
Low levels of potassium or magnesium in the blood may increase the risk of QT prolongation. Using certain drugs like diuretics or having conditions like severe sweating, diarrhea, or vomiting can also increase this risk.
Using tacrolimus may increase the likelihood of developing skin cancer. As such, limit your time in the sun, avoid tanning booths and sunlamps, and use sunscreen and protective clothing when outdoors.
Tacrolimus can increase the risk of infections or worsen any current infections. Avoid contact with people who have infections that may spread to others, such as chickenpox, measles, or flu. Inform your doctor if you have been exposed to an infection or need more information.
Before having any immunizations or vaccinations, tell your healthcare provider that you are using tacrolimus. Avoid contact with people who have recently received live vaccines, such as the flu vaccine that is inhaled through the nose.
This medication may increase your potassium levels. Before using potassium supplements or salt substitutes containing potassium, consult your doctor or pharmacist.
Older adults may be more sensitive to the side effects of this drug, particularly QT prolongation.
Since tacrolimus can be absorbed through the skin and lungs, it can harm an unborn baby. Women who are pregnant or may become pregnant should not handle this medication or breathe the dust from the capsules. Inform your doctor if you are pregnant or plan to become pregnant. Men and women using this medication should ask about reliable forms of birth control before and while using this medication. If you or your partner becomes pregnant, talk to your doctor immediately about the risks and benefits of this medication. Do not stop using this medication without consulting your doctor.
This medication can pass into breast milk and its effects on nursing infants are unknown. Discuss the risks and benefits with your doctor before breastfeeding.
Form and Strength
Prograf is available in the following forms and strengths:
Prograf
tacrolimus
FAQ
Do you take Prograf for life?
You might have to take this medicine for the rest of your life to prevent your body from rejecting the transplant.
Is Prograf a high risk drug?
Using Prograf may increase your risk of developing serious infections or certain types of cancer, such as lymphoma or skin cancer.
Prescription Required 
Formulation :
